Quinidine Syncope

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Quinidine-induced Syncope.

Since quinidine was introduced by Frey in 1918 it has remained the drug of choice for the conversion of certain arrhythmias to sinus rhythm and for the maintenance of normal rhythm once achieved. It is commonly used in this manner for atrial fibrillation, atrial flutter, -paroxysmal tachycardia of atrial, nodal, and ventricular origin, and ventriculat fibrillation. It has also been employed as ...

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Quinidine Syncope. Paroxysmal Ventricular Fibrillation Occurring during Treatment of Chronic Atrial Arrhythmias.

QUINIDINE occupies an almost unique place in the therapy of cardiac arrhythmias. In the 45-odd years of its clinical use only very few drugs possessing similar pharmacologic properties have been found, but none could match quinidine in its broad therapeutic applications. Consequently, the knowledge concerning its clinical use and toxicity is of considerable importance, for patients who tolerate...

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Syncope.

Syncope is a common clinical presentation. Although most commonly benign, it may herald a pathology with a poor prognosis. The work-up of syncope includes a careful history, physical examination, electrocardiogram, risk stratification, and appropriately directed testing. The key factor in the investigation of syncope is the presence (or absence) of structural heart disease or an abnormal electr...

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Syncope.

Syncope is a common presenting symptom, and is often a challenging diagnostic dilemma because of its various underlying causes. A careful initial clinical assessment with directed investigations is crucial in arriving at a presumptive diagnosis. Prolonged cardiac monitoring technologies have improved diagnostic accuracy in the more difficult cases.

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Quinidine-induced reversible pneumonitis.

We report a patient who developed fever and rapidly progressing lung infiltrates 4 days after the beginning of continuous quinidine sulfate therapy. The fever disappeared during the following 48 h and the pneumonitis slowly resolved over the next month once quinidine therapy was stopped. The diagnosis of quinidine-induced pneumonitis, which has not previously been reported in the literature (to...

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ژورنال

عنوان ژورنال: Circulation

سال: 1964

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.30.1.17